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Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care
BACKGROUND: There is increasing concern among primary care practitioners about the use of opioids for chronic pain, including their adverse effects, but little attention has been given to how reports of side effects from prescription medication can contribute to outcomes among patients with chronic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770177/ https://www.ncbi.nlm.nih.gov/pubmed/29392205 http://dx.doi.org/10.1097/PR9.0000000000000589 |
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author | Jamison, Robert N. Dorado, Kathleen Mei, Anna Edwards, Robert R. Martel, Marc O. |
author_facet | Jamison, Robert N. Dorado, Kathleen Mei, Anna Edwards, Robert R. Martel, Marc O. |
author_sort | Jamison, Robert N. |
collection | PubMed |
description | BACKGROUND: There is increasing concern among primary care practitioners about the use of opioids for chronic pain, including their adverse effects, but little attention has been given to how reports of side effects from prescription medication can contribute to outcomes among patients with chronic pain. The aim of this study was to investigate the impact of frequently reported side effects on mood, disability, and opioid misuse in patients with chronic pain prescribed opioids within primary care. METHODS: Two hundred (N = 200) patients with chronic pain taking opioids for pain were recruited into the study. All patients completed baseline measures and a monthly side effects checklist once a month for 6 months. Patients were divided evenly based on a median split of the number of endorsed side effects over 6 months. The subjects repeated the baseline measures at the end of the study period. RESULTS: Over time, reports of medication side effects tended to decrease, but differences in frequency of reported side effects from baseline to follow-up (6-month time) were not significant, and the order of the frequency of the reported side effects remained similar. Patients who reported significant medication-related adverse effects reported significantly greater activity interference, negative affect, and catastrophizing compared with those with fewer side effects (P < 0.01). In addition, those patients with pain who reported more side effects showed significantly higher scores on opioid misuse risk (P < 0.001). DISCUSSION: This study demonstrates the important role of monitoring medication-related side effects among patients with chronic pain who are prescribed opioid medication for pain within primary care. |
format | Online Article Text |
id | pubmed-5770177 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Wolters Kluwer |
record_format | MEDLINE/PubMed |
spelling | pubmed-57701772018-02-01 Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care Jamison, Robert N. Dorado, Kathleen Mei, Anna Edwards, Robert R. Martel, Marc O. Pain Rep General Section BACKGROUND: There is increasing concern among primary care practitioners about the use of opioids for chronic pain, including their adverse effects, but little attention has been given to how reports of side effects from prescription medication can contribute to outcomes among patients with chronic pain. The aim of this study was to investigate the impact of frequently reported side effects on mood, disability, and opioid misuse in patients with chronic pain prescribed opioids within primary care. METHODS: Two hundred (N = 200) patients with chronic pain taking opioids for pain were recruited into the study. All patients completed baseline measures and a monthly side effects checklist once a month for 6 months. Patients were divided evenly based on a median split of the number of endorsed side effects over 6 months. The subjects repeated the baseline measures at the end of the study period. RESULTS: Over time, reports of medication side effects tended to decrease, but differences in frequency of reported side effects from baseline to follow-up (6-month time) were not significant, and the order of the frequency of the reported side effects remained similar. Patients who reported significant medication-related adverse effects reported significantly greater activity interference, negative affect, and catastrophizing compared with those with fewer side effects (P < 0.01). In addition, those patients with pain who reported more side effects showed significantly higher scores on opioid misuse risk (P < 0.001). DISCUSSION: This study demonstrates the important role of monitoring medication-related side effects among patients with chronic pain who are prescribed opioid medication for pain within primary care. Wolters Kluwer 2017-03-06 /pmc/articles/PMC5770177/ /pubmed/29392205 http://dx.doi.org/10.1097/PR9.0000000000000589 Text en Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The International Association for the Study of Pain. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | General Section Jamison, Robert N. Dorado, Kathleen Mei, Anna Edwards, Robert R. Martel, Marc O. Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care |
title | Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care |
title_full | Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care |
title_fullStr | Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care |
title_full_unstemmed | Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care |
title_short | Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care |
title_sort | influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care |
topic | General Section |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770177/ https://www.ncbi.nlm.nih.gov/pubmed/29392205 http://dx.doi.org/10.1097/PR9.0000000000000589 |
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