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Biomechanical Rigidity and Quantitative Proteomics Analysis of Segmental Regions of the Trabecular Meshwork at Physiologic and Elevated Pressures

PURPOSE: The extracellular matrix (ECM) of the trabecular meshwork (TM) modulates resistance to aqueous humor outflow, thereby regulating IOP. Glaucoma, a leading cause of irreversible blindness worldwide, is associated with changes in the ECM of the TM. The elastic modulus of glaucomatous TM is lar...

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Detalles Bibliográficos
Autores principales:	Vranka, Janice A., Staverosky, Julia A., Reddy, Ashok P., Wilmarth, Phillip A., David, Larry L., Acott, Ted S., Russell, Paul, Raghunathan, Vijay Krishna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2018
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770183/ https://www.ncbi.nlm.nih.gov/pubmed/29340639 http://dx.doi.org/10.1167/iovs.17-22759

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