Increased surface expression of HIV-1 envelope is associated with improved antibody response in vaccinia prime/protein boost immunization

HIV-1 envelope (Env)-based vaccines have so far largely failed to induce antibodies that prevent HIV-1 infection. One factor proposed to limit the immunogenicity of cell-associated Env is its low level of expression on the cell surface, restricting accessibility to antibodies. Using a vaccinia prime...

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Detalles Bibliográficos
Autores principales: Hogan, Michael J., Conde-Motter, Angela, Jordan, Andrea P.O., Yang, Lifei, Cleveland, Brad, Guo, Wenjin, Romano, Josephine, Ni, Houping, Pardi, Norbert, LaBranche, Celia C., Montefiori, David C., Hu, Shiu-Lok, Hoxie, James A., Weissman, Drew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770335/
https://www.ncbi.nlm.nih.gov/pubmed/29175625
http://dx.doi.org/10.1016/j.virol.2017.10.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770335/
https://www.ncbi.nlm.nih.gov/pubmed/29175625
http://dx.doi.org/10.1016/j.virol.2017.10.013

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