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A perspective on multi-target drug discovery and design for complex diseases

Diseases of infection, of neurodegeneration (such as Alzheimer’s and Parkinson’s diseases), and of malignancy (cancers) have complex and varied causative factors. Modern drug discovery has the power to identify potential modulators for multiple targets from millions of compounds. Computational appro...

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Detalles Bibliográficos
Autores principales: Ramsay, Rona R., Popovic-Nikolic, Marija R., Nikolic, Katarina, Uliassi, Elisa, Bolognesi, Maria Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770353/
https://www.ncbi.nlm.nih.gov/pubmed/29340951
http://dx.doi.org/10.1186/s40169-017-0181-2