Cargando…

Cerebral Ischemia Increases Small Ubiquitin-Like Modifier Conjugation within Human Penumbral Tissue: Radiological–Pathological Correlation

Posttranslational modification by small ubiquitin-like modifier (SUMO) regulates myriad physiological processes within cells and has been demonstrated to be highly activated in murine brains after cerebral ischemia. Numerous in vitro and murine in vivo studies have demonstrated that this increased S...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bernstock, Joshua D., Ye, Daniel G., Griffin, Allison, Lee, Yang-ja, Lynch, John, Latour, Lawrence L., Friedman, Gregory K., Maric, Dragan, Hallenbeck, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770374/ https://www.ncbi.nlm.nih.gov/pubmed/29375471 http://dx.doi.org/10.3389/fneur.2017.00738

Ejemplares similares

Global Protein Conjugation by Ubiquitin-Like-Modifiers during Ischemic Stress Is Regulated by MicroRNAs and Confers Robust Tolerance to Ischemia
por: Lee, Yang-ja, et al.
Publicado: (2012)

Elevated Global SUMOylation in Ubc9 Transgenic Mice Protects Their Brains against Focal Cerebral Ischemic Damage
por: Lee, Yang-ja, et al.
Publicado: (2011)

A novel quantitative high-throughput screen identifies drugs that both activate SUMO conjugation via the inhibition of microRNAs 182 and 183 and facilitate neuroprotection in a model of oxygen and glucose deprivation
por: Bernstock, Joshua D, et al.
Publicado: (2015)

A Genome-Wide Analysis of the Penumbral Volume in Inbred Mice following Middle Cerebral Artery Occlusion
por: Rudy, Robert F., et al.
Publicado: (2019)

Platelets and lymphocytes drive progressive penumbral tissue loss during middle cerebral artery occlusion in mice
por: Schuhmann, Michael K., et al.
Publicado: (2021)

Optimizing Cardiac Out-Put to Increase Cerebral Penumbral Perfusion in Large Middle Cerebral Artery Ischemic Lesion—OPTIMAL Study
por: Fuhrer, Hannah, et al.
Publicado: (2017)

Blood Pressure and Penumbral Sustenance in Stroke from Large Vessel Occlusion
por: Regenhardt, Robert W., et al.
Publicado: (2017)

Selective Stimulation of Penumbral Cones Reveals Perception in the Shadow of Retinal Blood Vessels
por: Spitschan, Manuel, et al.
Publicado: (2015)

Microfluidic Model to Evaluate Astrocyte Activation in Penumbral Region following Ischemic Stroke
por: Denecke, Kathryn M., et al.
Publicado: (2022)

Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels
por: Lee, Yang-ja, et al.
Publicado: (2018)

Topotecan is a potent inhibitor of SUMOylation in glioblastoma multiforme and alters both cellular replication and metabolic programming
por: Bernstock, Joshua D., et al.
Publicado: (2017)

Drugging SUMOylation for neuroprotection and oncotherapy
por: Bernstock, Joshua D., et al.
Publicado: (2018)

Global SUMOylation is a molecular mechanism underlying hypothermia-induced ischemic tolerance
por: Lee, Yang-ja, et al.
Publicado: (2014)

Penumbral Imaging-Based Thrombolysis with Tenecteplase Is Feasible up to 24 Hours after Symptom Onset
por: Kate, Mahesh, et al.
Publicado: (2018)

Penumbral Imaging-Based Thrombolysis with Tenecteplase Is Feasible up to 24 Hours after Symptom Onset
por: Kate, Mahesh, et al.
Publicado: (2018)

Effect of different thresholds for CT perfusion volumetric analysis on estimated ischemic core and penumbral volumes
por: Karhi, Simo, et al.
Publicado: (2021)

Synthetic Oligodeoxynucleotides Containing Multiple Telemeric TTAGGG Motifs Suppress Inflammasome Activity in Macrophages Subjected to Oxygen and Glucose Deprivation and Reduce Ischemic Brain Injury in Stroke-Prone Spontaneously Hypertensive Rats
por: Zhao, Jing, et al.
Publicado: (2015)

Downstream Toll-like receptor signaling mediates adaptor-specific cytokine expression following focal cerebral ischemia
por: Famakin, Bolanle, et al.
Publicado: (2012)

Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets
por: Bedford, Lynn, et al.
Publicado: (2010)

SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke
por: Bernstock, Joshua D., et al.
Publicado: (2019)

Hyperglycaemia, Insulin Therapy and Critical Penumbral Regions for Prognosis in Acute Stroke: Further Insights from the INSULINFARCT Trial
por: Rosso, Charlotte, et al.
Publicado: (2015)

Quantitative Proteomics Reveals the Beneficial Effects of Low Glucose on Neuronal Cell Survival in an in vitro Ischemic Penumbral Model
por: Li, Hua, et al.
Publicado: (2020)

The Relationship Between Penumbral Tissue and Blood-Brain Barrier Disruption in Acute Stroke Patients Presenting in an Extended Time Window
por: Heidari, Parisa, et al.
Publicado: (2020)

The Role of Ubiquitin-Proteasome Pathway and Autophagy-Lysosome Pathway in Cerebral Ischemia
por: Chen, Chunli, et al.
Publicado: (2020)

Endovascular stroke treatment using balloon guide catheters may reduce penumbral tissue damage and improve long-term outcome
por: Berndt, Maria T., et al.
Publicado: (2020)

Ubiquitin-Specific Protease 29 Exacerbates Cerebral Ischemia-Reperfusion Injury in Mice
por: Hou, Jia-Bao, et al.
Publicado: (2021)

Ubiquitin-Conjugating Enzymes in Cancer
por: Bui, Quyen Thu, et al.
Publicado: (2021)

Crystal Structure of a Ube2S-Ubiquitin Conjugate
por: Lorenz, Sonja, et al.
Publicado: (2016)

The Ubiquitin Conjugating Enzyme: An Important Ubiquitin Transfer Platform in Ubiquitin-Proteasome System
por: Liu, Weigang, et al.
Publicado: (2020)

Interleukin-1α expression precedes IL-1β after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues
por: Luheshi, Nadia M, et al.
Publicado: (2011)

An inhibitor of ubiquitin conjugation and aggresome formation
por: An, Heeseon, et al.
Publicado: (2015)

UUCD: a family-based database of ubiquitin and ubiquitin-like conjugation
por: Gao, Tianshun, et al.
Publicado: (2013)

E3 Ubiquitin Ligase FBXO3 Drives Neuroinflammation to Aggravate Cerebral Ischemia/Reperfusion Injury
por: Gao, Yu, et al.
Publicado: (2022)

Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes
por: Xu, Zhen, et al.
Publicado: (2008)

What Was the Set of Ubiquitin and Ubiquitin-Like Conjugating Enzymes in the Eukaryote Common Ancestor?
por: Michelle, Caroline, et al.
Publicado: (2009)

Regulation of the DNA damage response by ubiquitin conjugation
por: Brinkmann, Kerstin, et al.
Publicado: (2015)

Natural Product Inhibitors of Ubiquitin Conjugation and Deconjugation
por: Hess, Wilfried, et al.
Publicado: (2016)

Immunoreactive Cells After Cerebral Ischemia
por: Wang, Yijie, et al.
Publicado: (2019)

Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import
por: Plafker, Scott M., et al.
Publicado: (2004)

iUUCD 2.0: an update with rich annotations for ubiquitin and ubiquitin-like conjugations
por: Zhou, Jiaqi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_0hhp9uqdecqhmqpl32r6l4bb2o