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Role of Macromolecular Crowding on the Intracellular Diffusion of DNA Binding Proteins
Recent experiments suggest that cellular crowding facilitates the target search dynamics of proteins on DNA, the mechanism of which is not yet known. By using large scale computer simulations, we show that two competing factors, namely the width of the depletion layer that separates the crowder clou...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770392/ https://www.ncbi.nlm.nih.gov/pubmed/29339733 http://dx.doi.org/10.1038/s41598-017-18933-3 |