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Dinuclear PhosphoiminoBINOL-Pd Container for Malononitrile: Catalytic Asymmetric Double Mannich Reaction for Chiral 1,3-Diamine Synthesis

A phosphoiminoBINOL ligand was designed to form a dinuclear metal complex that could hold a malononitrile molecule. The dinuclear bis(phosphoimino)binaphthoxy-Pd(2)(OAc)(2) complex catalyzed a double Mannich reaction of N-Boc-imines with malononitrile to give chiral 1,3-diamines with high enantiosel...

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Detalles Bibliográficos
Autores principales:	Arai, Takayoshi, Sato, Katsuya, Nakamura, Ayu, Makino, Hiroki, Masu, Hyuma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770441/ https://www.ncbi.nlm.nih.gov/pubmed/29339816 http://dx.doi.org/10.1038/s41598-018-19178-4

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