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The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2

Impaired or excessive growth of endothelial cells contributes to several diseases. However, the functional involvement of regulatory long non-coding RNAs in these processes is not well defined. Here, we show that the long non-coding antisense transcript of GATA6 (GATA6-AS) interacts with the epigene...

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Detalles Bibliográficos
Autores principales: Neumann, Philipp, Jaé, Nicolas, Knau, Andrea, Glaser, Simone F., Fouani, Youssef, Rossbach, Oliver, Krüger, Marcus, John, David, Bindereif, Albrecht, Grote, Phillip, Boon, Reinier A., Dimmeler, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770451/
https://www.ncbi.nlm.nih.gov/pubmed/29339785
http://dx.doi.org/10.1038/s41467-017-02431-1