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A prebiotic template-directed peptide synthesis based on amyloids

The prebiotic replication of information-coding molecules is a central problem concerning life’s origins. Here, we report that amyloids composed of short peptides can direct the sequence-selective, regioselective and stereoselective condensation of amino acids. The addition of activated DL-arginine...

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Detalles Bibliográficos
Autores principales: Rout, Saroj K., Friedmann, Michael P., Riek, Roland, Greenwald, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770463/
https://www.ncbi.nlm.nih.gov/pubmed/29339755
http://dx.doi.org/10.1038/s41467-017-02742-3

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