Cargando…
A prebiotic template-directed peptide synthesis based on amyloids
The prebiotic replication of information-coding molecules is a central problem concerning life’s origins. Here, we report that amyloids composed of short peptides can direct the sequence-selective, regioselective and stereoselective condensation of amino acids. The addition of activated DL-arginine...
Autores principales: | Rout, Saroj K., Friedmann, Michael P., Riek, Roland, Greenwald, Jason |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770463/ https://www.ncbi.nlm.nih.gov/pubmed/29339755 http://dx.doi.org/10.1038/s41467-017-02742-3 |
Ejemplares similares
-
Prebiotically Plausible Autocatalytic Peptide Amyloids
por: Rout, Saroj K., et al.
Publicado: (2021) -
Towards Prebiotic Catalytic Amyloids Using High Throughput Screening
por: Friedmann, Michael P., et al.
Publicado: (2015) -
Deep Eutectic Solvents as Media for the Prebiotic DNA-Templated Synthesis of Peptides
por: Núñez-Pertíñez, Samuel, et al.
Publicado: (2020) -
An Analysis of Nucleotide–Amyloid
Interactions
Reveals Selective Binding to Codon-Sized RNA
por: Rout, Saroj K., et al.
Publicado: (2023) -
Templated replication (or lack thereof) under prebiotically pertinent conditions
por: Bapat, Niraja V., et al.
Publicado: (2018)