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Squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution

Lichen planus (LP) is a relatively common mucocutaneous disease with autoimmune etiology. Considering its malignancy potential, it is important to define the correct diagnosis, treatment, and clinical follow-up for patients with LP so that the disease is not diagnosed late, thus hindering the chance...

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Autores principales: Silveira, Wanessa da Silva, Bottezini, Ezequiel Gregolin, Linden, Maria Salete, Rinaldi, Isadora, Paranhos, Luiz Renato, de Carli, João Paulo, Trentin, Micheline, dos Santos, Pâmela Letícia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Oral and Maxillofacial Surgeons 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770472/
https://www.ncbi.nlm.nih.gov/pubmed/29354593
http://dx.doi.org/10.5125/jkaoms.2017.43.S1.S14
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author Silveira, Wanessa da Silva
Bottezini, Ezequiel Gregolin
Linden, Maria Salete
Rinaldi, Isadora
Paranhos, Luiz Renato
de Carli, João Paulo
Trentin, Micheline
dos Santos, Pâmela Letícia
author_facet Silveira, Wanessa da Silva
Bottezini, Ezequiel Gregolin
Linden, Maria Salete
Rinaldi, Isadora
Paranhos, Luiz Renato
de Carli, João Paulo
Trentin, Micheline
dos Santos, Pâmela Letícia
author_sort Silveira, Wanessa da Silva
collection PubMed
description Lichen planus (LP) is a relatively common mucocutaneous disease with autoimmune etiology. Considering its malignancy potential, it is important to define the correct diagnosis, treatment, and clinical follow-up for patients with LP so that the disease is not diagnosed late, thus hindering the chances of curing the disease. This study aims to describe a clinical case of oral squamous cell carcinoma, potentially originated from LP. The patient is undergoing clinical and histopathological follow-up. A 64-year-old Caucasian male patient presented with a proliferative verrucous lesion on the tongue and sought treatment at the School of Dentistry, University of Passo Fundo (UPF), Passo Fundo, Brazil. He claimed the lesion had been present since 1988, and had been initially diagnoses as “oral lichen planus.” The physical exam presented three diagnostic hypotheses: plaque-like oral LP, verrucous carcinoma, and squamous cell carcinoma. After incisional biopsy and histopathological analysis, squamous cell carcinoma was diagnosed, probably originating from oral LP. The case study shows that malignancy from oral LP is possible, which justifies periodic clinical and histopathological follow-up, as well as the elimination of risk factors for carcinoma in patients with oral LP.
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spelling pubmed-57704722018-01-21 Squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution Silveira, Wanessa da Silva Bottezini, Ezequiel Gregolin Linden, Maria Salete Rinaldi, Isadora Paranhos, Luiz Renato de Carli, João Paulo Trentin, Micheline dos Santos, Pâmela Letícia J Korean Assoc Oral Maxillofac Surg Case Report Lichen planus (LP) is a relatively common mucocutaneous disease with autoimmune etiology. Considering its malignancy potential, it is important to define the correct diagnosis, treatment, and clinical follow-up for patients with LP so that the disease is not diagnosed late, thus hindering the chances of curing the disease. This study aims to describe a clinical case of oral squamous cell carcinoma, potentially originated from LP. The patient is undergoing clinical and histopathological follow-up. A 64-year-old Caucasian male patient presented with a proliferative verrucous lesion on the tongue and sought treatment at the School of Dentistry, University of Passo Fundo (UPF), Passo Fundo, Brazil. He claimed the lesion had been present since 1988, and had been initially diagnoses as “oral lichen planus.” The physical exam presented three diagnostic hypotheses: plaque-like oral LP, verrucous carcinoma, and squamous cell carcinoma. After incisional biopsy and histopathological analysis, squamous cell carcinoma was diagnosed, probably originating from oral LP. The case study shows that malignancy from oral LP is possible, which justifies periodic clinical and histopathological follow-up, as well as the elimination of risk factors for carcinoma in patients with oral LP. The Korean Association of Oral and Maxillofacial Surgeons 2017-12 2017-12-27 /pmc/articles/PMC5770472/ /pubmed/29354593 http://dx.doi.org/10.5125/jkaoms.2017.43.S1.S14 Text en Copyright © 2017 The Korean Association of Oral and Maxillofacial Surgeons. http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Silveira, Wanessa da Silva
Bottezini, Ezequiel Gregolin
Linden, Maria Salete
Rinaldi, Isadora
Paranhos, Luiz Renato
de Carli, João Paulo
Trentin, Micheline
dos Santos, Pâmela Letícia
Squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution
title Squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution
title_full Squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution
title_fullStr Squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution
title_full_unstemmed Squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution
title_short Squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution
title_sort squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770472/
https://www.ncbi.nlm.nih.gov/pubmed/29354593
http://dx.doi.org/10.5125/jkaoms.2017.43.S1.S14
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