Therapeutic targeting of CK2 in acute and chronic leukemias

CK2 is a ubiquitously expressed, constitutively active Ser/Thr protein kinase, which is considered the most pleiotropic protein kinase in the human kinome. Such a pleiotropy explains the involvement of CK2 in many cellular events. However, its predominant roles are stimulation of cell growth and pre...

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Detalles Bibliográficos
Autores principales: Buontempo, F, McCubrey, J A, Orsini, E, Ruzzene, M, Cappellini, A, Lonetti, A, Evangelisti, C, Chiarini, F, Barata, J T, Martelli, A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770594/
https://www.ncbi.nlm.nih.gov/pubmed/28951560
http://dx.doi.org/10.1038/leu.2017.301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770594/
https://www.ncbi.nlm.nih.gov/pubmed/28951560
http://dx.doi.org/10.1038/leu.2017.301

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