Cargando…

The Beta Adrenergic Receptor Blocker Propranolol Counteracts Retinal Dysfunction in a Mouse Model of Oxygen Induced Retinopathy: Restoring the Balance between Apoptosis and Autophagy

In a mouse model of oxygen induced retinopathy (OIR), beta adrenergic receptor (BAR) blockade has been shown to recover hypoxia-associated retinal damages. Although the adrenergic signaling is an important regulator of apoptotic and autophagic processes, the role of BARs in retinal cell death remain...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cammalleri, Maurizio, Locri, Filippo, Catalani, Elisabetta, Filippi, Luca, Cervia, Davide, Dal Monte, Massimo, Bagnoli, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770647/ https://www.ncbi.nlm.nih.gov/pubmed/29375312 http://dx.doi.org/10.3389/fncel.2017.00395

Ejemplares similares

Protective Efficacy of a Dietary Supplement Based on Forskolin, Homotaurine, Spearmint Extract, and Group B Vitamins in a Mouse Model of Optic Nerve Injury
por: Locri, Filippo, et al.
Publicado: (2019)

Further Evidence on Efficacy of Diet Supplementation with Fatty Acids in Ocular Pathologies: Insights from the EAE Model of Optic Neuritis
por: Locri, Filippo, et al.
Publicado: (2018)

Diabetic Retinopathy in the Spontaneously Diabetic Torii Rat: Pathogenetic Mechanisms and Preventive Efficacy of Inhibiting the Urokinase-Type Plasminogen Activator Receptor System
por: Cammalleri, Maurizio, et al.
Publicado: (2017)

Potential role of the methylation of VEGF gene promoter in response to hypoxia in oxygen‐induced retinopathy: beneficial effect of the absence of AQP4
por: Pisani, Francesco, et al.
Publicado: (2017)

Gaining insight on mitigation of rubeosis iridis by UPARANT in a mouse model associated with proliferative retinopathy
por: Locri, Filippo, et al.
Publicado: (2020)

Fatty Acids Dietary Supplements Exert Anti-Inflammatory Action and Limit Ganglion Cell Degeneration in the Retina of the EAE Mouse Model of Multiple Sclerosis
por: Dal Monte, Massimo, et al.
Publicado: (2018)

Lisosan G Protects the Retina from Neurovascular Damage in Experimental Diabetic Retinopathy
por: Amato, Rosario, et al.
Publicado: (2018)

Novel Insights into Beta 2 Adrenergic Receptor Function in the rd10 Model of Retinitis Pigmentosa
por: Cammalleri, Maurizio, et al.
Publicado: (2020)

The urokinase‐type plasminogen activator system as drug target in retinitis pigmentosa: New pre‐clinical evidence in the rd10 mouse model
por: Cammalleri, Maurizio, et al.
Publicado: (2019)

Efficacy of a Fatty Acids Dietary Supplement in a Polyethylene Glycol-Induced Mouse Model of Retinal Degeneration
por: Cammalleri, Maurizio, et al.
Publicado: (2017)

Decoupling Oxygen Tension From Retinal Vascularization as a New Perspective for Management of Retinopathy of Prematurity. New Opportunities From β-adrenoceptors
por: Filippi, Luca, et al.
Publicado: (2022)

UPARANT is an effective antiangiogenic agent in a mouse model of rubeosis iridis
por: Locri, Filippo, et al.
Publicado: (2019)

Diabetic retinopathy: a matter of retinal ganglion cell homeostasis
por: Catalani, Elisabetta, et al.
Publicado: (2020)

β3‐Adrenoceptor, a novel player in the round‐trip from neonatal diseases to cancer: Suggestive clues from embryo
por: Filippi, Luca, et al.
Publicado: (2021)

Restored retinal physiology after administration of niacin with citicoline in a mouse model of hypertensive glaucoma
por: Melecchi, Alberto, et al.
Publicado: (2023)

Neurosensory Alterations in Retinopathy of Prematurity: A Window to Neurological Impairments Associated to Preterm Birth
por: Lucchesi, Martina, et al.
Publicado: (2022)

Study protocol: safety and efficacy of propranolol in newborns with Retinopathy of Prematurity (PROP-ROP): ISRCTN18523491
por: Filippi, Luca, et al.
Publicado: (2010)

A Dietary Combination of Forskolin with Homotaurine, Spearmint and B Vitamins Protects Injured Retinal Ganglion Cells in a Rodent Model of Hypertensive Glaucoma
por: Cammalleri, Maurizio, et al.
Publicado: (2020)

Propranolol 0.2% Eye Micro-Drops for Retinopathy of Prematurity: A Prospective Phase IIB Study
por: Filippi, Luca, et al.
Publicado: (2019)

Oxidative Stress Induces a VEGF Autocrine Loop in the Retina: Relevance for Diabetic Retinopathy
por: Rossino, Maria Grazia, et al.
Publicado: (2020)

Refractive Outcome in Preterm Newborns With ROP After Propranolol Treatment. A Retrospective Observational Cohort Study
por: Filippi, Luca, et al.
Publicado: (2019)

Novel emphasis on somatostatinergic system in retinal ganglion cell neuroresilience
por: Catalani, Elisabetta, et al.
Publicado: (2023)

The uPAR System as a Potential Therapeutic Target in the Diseased Eye
por: Cammalleri, Maurizio, et al.
Publicado: (2019)

Hypotensive Effect of Nanomicellar Formulation of Melatonin and Agomelatine in a Rat Model: Significance for Glaucoma Therapy
por: Dal Monte, Massimo, et al.
Publicado: (2020)

A Topical Formulation of Melatoninergic Compounds Exerts Strong Hypotensive and Neuroprotective Effects in a Rat Model of Hypertensive Glaucoma
por: Dal Monte, Massimo, et al.
Publicado: (2020)

Effects of Topical Gabapentin on Ocular Pain and Tear Secretion
por: Cammalleri, Maurizio, et al.
Publicado: (2021)

Preventive Efficacy of an Antioxidant Compound on Blood Retinal Barrier Breakdown and Visual Dysfunction in Streptozotocin-Induced Diabetic Rats
por: Canovai, Alessio, et al.
Publicado: (2022)

Increased efficacy of dietary supplement containing wax ester-rich marine oil and xanthophylls in a mouse model of dry macular degeneration
por: Melecchi, Alberto, et al.
Publicado: (2022)

HIF-1-Dependent Induction of β3 Adrenoceptor: Evidence from the Mouse Retina
por: Amato, Rosario, et al.
Publicado: (2022)

An imbalance in autophagy contributes to retinal damage in a rat model of oxygen‐induced retinopathy
por: Pesce, Noemi Anna, et al.
Publicado: (2021)

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma
por: Wolter, Jennifer K, et al.
Publicado: (2013)

Neuroprotective Peptides in Retinal Disease
por: Cervia, Davide, et al.
Publicado: (2019)

A Drosophila perspective on retina functions and dysfunctions
por: Catalani, Elisabetta, et al.
Publicado: (2021)

The β-adrenergic receptor blocker and anti-inflammatory drug propranolol mitigates brain cytokine expression in a long-term model of Gulf War Illness
por: Michalovicz, Lindsay T., et al.
Publicado: (2021)

Association of the Somatostatin Analog Octreotide With Magnetic Nanoparticles for Intraocular Delivery: A Possible Approach for the Treatment of Diabetic Retinopathy
por: Amato, Rosario, et al.
Publicado: (2020)

Liposome-Mediated Delivery Improves the Efficacy of Lisosan G against Retinopathy in Diabetic Mice
por: Amato, Rosario, et al.
Publicado: (2023)

Nutraceutical Strategy to Counteract Eye Neurodegeneration and Oxidative Stress in Drosophila melanogaster Fed with High-Sugar Diet
por: Catalani, Elisabetta, et al.
Publicado: (2021)

Mechanoenzymology in the Kinetic Resolution of β-Blockers: Propranolol as a Case Study
por: Gamboa-Velázquez, Gonzalo, et al.
Publicado: (2022)

Perioperative adrenergic response and the use of beta-blockers
por: Kim, Tae-Yop
Publicado: (2014)

Dietary Supplementation of Antioxidant Compounds Prevents Light-Induced Retinal Damage in a Rat Model
por: Amato, Rosario, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_v5a9njmnmhrq9v0g3o0holg2s8