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Vaccine Delivery: Turning the Old Adjuvant from Gel to Nanoparticles to Amplify CD8(+) T Cell Responses (Adv. Sci. 1/2018)
Alum, the well‐known vaccine adjuvant with a long history of clinical use, is changed from a “gel” to nanoparticles. This changes its mechanism of action from a “depot” that resides at the injection site, to nanoparticles that transport antigen and adjuvant into the lymph node. As reported by Xun Su...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770673/ http://dx.doi.org/10.1002/advs.201870001 |