Cargando…

Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type‐1 insulin‐like growth factor receptors in neuronal cells

Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with synaptic dysfunction, pathological accumulation of β‐amyloid (Aβ), and neuronal loss. The self‐association of Aβ monomers into soluble oligomers seems to be crucial for the development of neurotoxicity (J. Neur...

Descripción completa

Detalles Bibliográficos
Autores principales: Zimbone, Stefania, Monaco, Irene, Gianì, Fiorenza, Pandini, Giuseppe, Copani, Agata G., Giuffrida, Maria Laura, Rizzarelli, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770784/
https://www.ncbi.nlm.nih.gov/pubmed/29094448
http://dx.doi.org/10.1111/acel.12684