Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach

Pseudomonas aeruginosa is an opportunistic pathogen which uses a number of strategies to cross epithelial and endothelial barriers at cell–cell junctions. In this review, we describe how the coordinated actions of P. aeruginosa's virulence factors trigger various molecular mechanisms to disarm...

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Detalles Bibliográficos
Autores principales: Golovkine, Guillaume, Reboud, Emeline, Huber, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770805/
https://www.ncbi.nlm.nih.gov/pubmed/29379773
http://dx.doi.org/10.3389/fcimb.2017.00532
Descripción
Sumario:Pseudomonas aeruginosa is an opportunistic pathogen which uses a number of strategies to cross epithelial and endothelial barriers at cell–cell junctions. In this review, we describe how the coordinated actions of P. aeruginosa's virulence factors trigger various molecular mechanisms to disarm the junctional gate responsible for tissue integrity.

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