Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach

Pseudomonas aeruginosa is an opportunistic pathogen which uses a number of strategies to cross epithelial and endothelial barriers at cell–cell junctions. In this review, we describe how the coordinated actions of P. aeruginosa's virulence factors trigger various molecular mechanisms to disarm...

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Detalles Bibliográficos
Autores principales: Golovkine, Guillaume, Reboud, Emeline, Huber, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770805/
https://www.ncbi.nlm.nih.gov/pubmed/29379773
http://dx.doi.org/10.3389/fcimb.2017.00532
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author Golovkine, Guillaume
Reboud, Emeline
Huber, Philippe
author_facet Golovkine, Guillaume
Reboud, Emeline
Huber, Philippe
author_sort Golovkine, Guillaume
collection PubMed
description Pseudomonas aeruginosa is an opportunistic pathogen which uses a number of strategies to cross epithelial and endothelial barriers at cell–cell junctions. In this review, we describe how the coordinated actions of P. aeruginosa's virulence factors trigger various molecular mechanisms to disarm the junctional gate responsible for tissue integrity.
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spelling pubmed-57708052018-01-29 Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach Golovkine, Guillaume Reboud, Emeline Huber, Philippe Front Cell Infect Microbiol Microbiology Pseudomonas aeruginosa is an opportunistic pathogen which uses a number of strategies to cross epithelial and endothelial barriers at cell–cell junctions. In this review, we describe how the coordinated actions of P. aeruginosa's virulence factors trigger various molecular mechanisms to disarm the junctional gate responsible for tissue integrity. Frontiers Media S.A. 2018-01-11 /pmc/articles/PMC5770805/ /pubmed/29379773 http://dx.doi.org/10.3389/fcimb.2017.00532 Text en Copyright © 2018 Golovkine, Reboud and Huber. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Golovkine, Guillaume
Reboud, Emeline
Huber, Philippe
Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach
title Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach
title_full Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach
title_fullStr Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach
title_full_unstemmed Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach
title_short Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach
title_sort pseudomonas aeruginosa takes a multi-target approach to achieve junction breach
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770805/
https://www.ncbi.nlm.nih.gov/pubmed/29379773
http://dx.doi.org/10.3389/fcimb.2017.00532
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AT reboudemeline pseudomonasaeruginosatakesamultitargetapproachtoachievejunctionbreach
AT huberphilippe pseudomonasaeruginosatakesamultitargetapproachtoachievejunctionbreach

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