Genome-Edited, TH-expressing Neuroblastoma Cells as a Disease Model for Dopamine-Related Disorders: A Proof-of-Concept Study on DJ-1-deficient Parkinsonism

Impairment of the dopaminergic (DA) system is a common cause of several movement disorders including Parkinson’s disease (PD), however, little is known about the underlying disease mechanisms. The recent development of stem-cell-based protocols for the generation of DA neurons partially solved this...

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Detalles Bibliográficos
Autores principales: Prasuhn, Jannik, Mårtensson, Christoph U., Krajka, Victor, Klein, Christine, Rakovic, Aleksandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770810/
https://www.ncbi.nlm.nih.gov/pubmed/29379417
http://dx.doi.org/10.3389/fncel.2017.00426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770810/
https://www.ncbi.nlm.nih.gov/pubmed/29379417
http://dx.doi.org/10.3389/fncel.2017.00426

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