Cargando…
PGC‐1α affects aging‐related changes in muscle and motor function by modulating specific exercise‐mediated changes in old mice
The age‐related impairment in muscle function results in a drastic decline in motor coordination and mobility in elderly individuals. Regular physical activity is the only efficient intervention to prevent and treat this age‐associated degeneration. However, the mechanisms that underlie the therapeu...
Autores principales: | Gill, Jonathan F., Santos, Gesa, Schnyder, Svenia, Handschin, Christoph |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770876/ https://www.ncbi.nlm.nih.gov/pubmed/29067788 http://dx.doi.org/10.1111/acel.12697 |
Ejemplares similares
-
Loss of Renal Tubular PGC-1α Exacerbates Diet-Induced Renal Steatosis and Age-Related Urinary Sodium Excretion in Mice
por: Svensson, Kristoffer, et al.
Publicado: (2016) -
PGC-1α expression in murine AgRP neurons regulates food intake and energy balance
por: Gill, Jonathan F., et al.
Publicado: (2016) -
Peroxisome proliferator‐activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging
por: Gill, Jonathan F., et al.
Publicado: (2019) -
PGC-1α Improves Glucose Homeostasis in Skeletal Muscle in an Activity-Dependent Manner
por: Summermatter, Serge, et al.
Publicado: (2013) -
PGC-1β modulates catabolism and fiber atrophy in the fasting-response of specific skeletal muscle beds
por: Schmid, Svenia, et al.
Publicado: (2022)