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Using Cystine Knot Proteins as a Novel Approach to Retarget Oncolytic Measles Virus
Modified measles virus (MV) has effective oncolytic activity preclinically and is currently being investigated in clinical trials for various types of cancer. We investigated the use of cystine knot proteins (CKPs) to direct MV activity. CKPs are short polypeptides that bind their targets with high...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society of Gene & Cell Therapy
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771132/ https://www.ncbi.nlm.nih.gov/pubmed/29367943 http://dx.doi.org/10.1016/j.omto.2017.09.005 |