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p66Shc gene expression in peripheral blood mononuclear cells and progression of diabetic complications

BACKGROUND: The risk of diabetic complications is modified by genetic and epigenetic factors. p66Shc drives the hyperglycaemic cell damage and its deletion prevents experimental diabetic complications. We herein tested whether p66Shc expression in peripheral blood mononuclear cells (PBMCs) predicts...

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Detalles Bibliográficos
Autores principales: Fadini, Gian Paolo, Albiero, Mattia, Bonora, Benedetta Maria, Poncina, Nicol, Vigili de Kreutzenberg, Saula, Avogaro, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771224/
https://www.ncbi.nlm.nih.gov/pubmed/29343271
http://dx.doi.org/10.1186/s12933-018-0660-9

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