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p66Shc gene expression in peripheral blood mononuclear cells and progression of diabetic complications
BACKGROUND: The risk of diabetic complications is modified by genetic and epigenetic factors. p66Shc drives the hyperglycaemic cell damage and its deletion prevents experimental diabetic complications. We herein tested whether p66Shc expression in peripheral blood mononuclear cells (PBMCs) predicts...
Autores principales: | Fadini, Gian Paolo, Albiero, Mattia, Bonora, Benedetta Maria, Poncina, Nicol, Vigili de Kreutzenberg, Saula, Avogaro, Angelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771224/ https://www.ncbi.nlm.nih.gov/pubmed/29343271 http://dx.doi.org/10.1186/s12933-018-0660-9 |
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