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miR-149 in Human Cancer: A Systemic Review
MicroRNAs (miRNAs) are small noncoding RNAs that regulate post-transcriptional gene expression via binding to the 3'-untranslated region (3'-UTR) of targeted mRNAs. They are reported to play important roles in tumorigenesis and progression of various cancers. Among them, miR-149 was confir...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771345/ https://www.ncbi.nlm.nih.gov/pubmed/29344284 http://dx.doi.org/10.7150/jca.21044 |
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author | He, Yunjie Yu, Dandan Zhu, Lingping Zhong, Shanliang Zhao, Jianhua Tang, Jinhai |
author_facet | He, Yunjie Yu, Dandan Zhu, Lingping Zhong, Shanliang Zhao, Jianhua Tang, Jinhai |
author_sort | He, Yunjie |
collection | PubMed |
description | MicroRNAs (miRNAs) are small noncoding RNAs that regulate post-transcriptional gene expression via binding to the 3'-untranslated region (3'-UTR) of targeted mRNAs. They are reported to play important roles in tumorigenesis and progression of various cancers. Among them, miR-149 was confirmed to be aberrantly regulated in various tumors. In this review, we provide a complex overview of miR-149, particularly summarize the critical roles of it in cancers and expect to lay the foundation for future works on this important microRNA. |
format | Online Article Text |
id | pubmed-5771345 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-57713452018-01-17 miR-149 in Human Cancer: A Systemic Review He, Yunjie Yu, Dandan Zhu, Lingping Zhong, Shanliang Zhao, Jianhua Tang, Jinhai J Cancer Review MicroRNAs (miRNAs) are small noncoding RNAs that regulate post-transcriptional gene expression via binding to the 3'-untranslated region (3'-UTR) of targeted mRNAs. They are reported to play important roles in tumorigenesis and progression of various cancers. Among them, miR-149 was confirmed to be aberrantly regulated in various tumors. In this review, we provide a complex overview of miR-149, particularly summarize the critical roles of it in cancers and expect to lay the foundation for future works on this important microRNA. Ivyspring International Publisher 2018-01-01 /pmc/articles/PMC5771345/ /pubmed/29344284 http://dx.doi.org/10.7150/jca.21044 Text en © Ivyspring International Publisher This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions. |
spellingShingle | Review He, Yunjie Yu, Dandan Zhu, Lingping Zhong, Shanliang Zhao, Jianhua Tang, Jinhai miR-149 in Human Cancer: A Systemic Review |
title | miR-149 in Human Cancer: A Systemic Review |
title_full | miR-149 in Human Cancer: A Systemic Review |
title_fullStr | miR-149 in Human Cancer: A Systemic Review |
title_full_unstemmed | miR-149 in Human Cancer: A Systemic Review |
title_short | miR-149 in Human Cancer: A Systemic Review |
title_sort | mir-149 in human cancer: a systemic review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771345/ https://www.ncbi.nlm.nih.gov/pubmed/29344284 http://dx.doi.org/10.7150/jca.21044 |
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