Association of Limb-Girdle muscular dystrophy with multiple sclerosis: A case report

BACKGROUND: The association of limb-girdle muscular dystrophy (LGMD) with other neurological disorders is uncommon. CASE PRESENTATION: We report a 25-year-old female with LGMD who suffered from slowly progressive proximal muscular weakness and atrophy since she was 12 years of age. The patient recen...

Descripción completa

Detalles Bibliográficos
Autores principales: Arzani, Mahsa, Rezaei, Hamed, Moghadasi, Abdorreza Naser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771368/
https://www.ncbi.nlm.nih.gov/pubmed/29387327
http://dx.doi.org/10.22088/cjim.9.1.96
_version_ 1783293254398115840
author Arzani, Mahsa
Rezaei, Hamed
Moghadasi, Abdorreza Naser
author_facet Arzani, Mahsa
Rezaei, Hamed
Moghadasi, Abdorreza Naser
author_sort Arzani, Mahsa
collection PubMed
description BACKGROUND: The association of limb-girdle muscular dystrophy (LGMD) with other neurological disorders is uncommon. CASE PRESENTATION: We report a 25-year-old female with LGMD who suffered from slowly progressive proximal muscular weakness and atrophy since she was 12 years of age. The patient recently presented with acute loss of left side visual acuity. After evaluation, findings were suggestive of multiple sclerosis. CONCLUSIONS: This is the first report of LGMD in association with MS. The simultaneous occurrence of MS with myopathies may be incidental but there may be a genetic susceptibility for both diseases. This comorbidity may influence the treatment of MS.
format Online
Article
Text
id pubmed-5771368
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Babol University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-57713682018-01-31 Association of Limb-Girdle muscular dystrophy with multiple sclerosis: A case report Arzani, Mahsa Rezaei, Hamed Moghadasi, Abdorreza Naser Caspian J Intern Med Case Report BACKGROUND: The association of limb-girdle muscular dystrophy (LGMD) with other neurological disorders is uncommon. CASE PRESENTATION: We report a 25-year-old female with LGMD who suffered from slowly progressive proximal muscular weakness and atrophy since she was 12 years of age. The patient recently presented with acute loss of left side visual acuity. After evaluation, findings were suggestive of multiple sclerosis. CONCLUSIONS: This is the first report of LGMD in association with MS. The simultaneous occurrence of MS with myopathies may be incidental but there may be a genetic susceptibility for both diseases. This comorbidity may influence the treatment of MS. Babol University of Medical Sciences 2018 /pmc/articles/PMC5771368/ /pubmed/29387327 http://dx.doi.org/10.22088/cjim.9.1.96 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Arzani, Mahsa
Rezaei, Hamed
Moghadasi, Abdorreza Naser
Association of Limb-Girdle muscular dystrophy with multiple sclerosis: A case report
title Association of Limb-Girdle muscular dystrophy with multiple sclerosis: A case report
title_full Association of Limb-Girdle muscular dystrophy with multiple sclerosis: A case report
title_fullStr Association of Limb-Girdle muscular dystrophy with multiple sclerosis: A case report
title_full_unstemmed Association of Limb-Girdle muscular dystrophy with multiple sclerosis: A case report
title_short Association of Limb-Girdle muscular dystrophy with multiple sclerosis: A case report
title_sort association of limb-girdle muscular dystrophy with multiple sclerosis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771368/
https://www.ncbi.nlm.nih.gov/pubmed/29387327
http://dx.doi.org/10.22088/cjim.9.1.96
work_keys_str_mv AT arzanimahsa associationoflimbgirdlemusculardystrophywithmultiplesclerosisacasereport
AT rezaeihamed associationoflimbgirdlemusculardystrophywithmultiplesclerosisacasereport
AT moghadasiabdorrezanaser associationoflimbgirdlemusculardystrophywithmultiplesclerosisacasereport

Ejemplares similares