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The Role of Sigma-1 Receptor, an Intracellular Chaperone in Neurodegenerative Diseases

BACKGROUND: Widespread protein aggregation occurs in the living system under stress or during aging, owing to disturbance of endoplasmic reticulum (ER) proteostasis. Many neurodegenerative diseases may have a common mechanism: the failure of protein homeostasis. Perturbation of ER results in unfolde...

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Detalles Bibliográficos
Autores principales:	Penke, Botond, Fülöp, Lívia, Szűcs, Mária, Frecska, Ede
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771390/ https://www.ncbi.nlm.nih.gov/pubmed/28554311 http://dx.doi.org/10.2174/1570159X15666170529104323

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