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Induction of high tolerance to artemisinin by sub-lethal administration: A new in vitro model of P. falciparum
Artemisinin resistance is a major threat to malaria control efforts. Resistance is characterized by an increase in the Plasmodium falciparum parasite clearance half-life following treatment with artemisinin-based combination therapies (ACTs) and an increase in the percentage of surviving parasites....
Autores principales: | De Lucia, Serena, Tsamesidis, Ioannis, Pau, Maria Carmina, Kesely, Kristina R., Pantaleo, Antonella, Turrini, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771598/ https://www.ncbi.nlm.nih.gov/pubmed/29342187 http://dx.doi.org/10.1371/journal.pone.0191084 |
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