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A game of substrates: replication fork remodeling and its roles in genome stability and chemo-resistance
During the hours that human cells spend in the DNA synthesis (S) phase of the cell cycle, they may encounter adversities such as DNA damage or shortage of nucleotides. Under these stresses, replication forks in DNA may experience slowing, stalling, and breakage. Fork remodeling mechanisms, which sta...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Shared Science Publishers OG
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771654/ https://www.ncbi.nlm.nih.gov/pubmed/29355244 http://dx.doi.org/10.15698/cst2017.12.114 |