DNA methylation alterations in the genome of a toddler with cri‐du‐chat syndrome

This manuscript reports on genomewide epigenetic alterations in cri‐du‐chat syndrome related to a partial aneusomy of chromosome 5. A systematic analysis of these alterations will open up new possibilities for the prognostic evaluation of CDCS patients and the development of new therapeutic interven...

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Detalles Bibliográficos
Autores principales: Naumova, Oxana Y., Rychkov, Sergey Y., Kuznetzova, Tatyana V., Odintsova, Veronika V., Kornilov, Sergey A., Grigorenko, Elena L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771924/
https://www.ncbi.nlm.nih.gov/pubmed/29375829
http://dx.doi.org/10.1002/ccr3.1274
Descripción
Sumario:This manuscript reports on genomewide epigenetic alterations in cri‐du‐chat syndrome related to a partial aneusomy of chromosome 5. A systematic analysis of these alterations will open up new possibilities for the prognostic evaluation of CDCS patients and the development of new therapeutic interventions for reducing the severity of the disease.

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