Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer’s disease at various cognitive stages

Synaptic loss, plaques and neurofibrillary tangles are viewed as hallmarks of Alzheimer’s disease (AD). This study investigated synaptic markers in neocortical Brodmann area 9 (BA9) samples from 171 subjects with and without AD at different levels of cognitive impairment. The expression levels of ve...

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Detalles Bibliográficos
Autores principales: Poirel, Odile, Mella, Sébastien, Videau, Catherine, Ramet, Lauriane, Davoli, Maria Antonietta, Herzog, Etienne, Katsel, Pavel, Mechawar, Naguib, Haroutunian, Vahram, Epelbaum, Jacques, Daumas, Stéphanie, El Mestikawy, Salah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772053/
https://www.ncbi.nlm.nih.gov/pubmed/29343737
http://dx.doi.org/10.1038/s41598-018-19154-y

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