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Small Bowel Diverticulosis and Jejunal Perforation in Marfan Syndrome
Marfan syndrome is an autosomal dominant disorder involving mutation in the FBN1 gene, which encodes fibrillin-1, a protein critical to maintain the integrity of connective tissue. A mutation in this gene can affect multiple organ systems, but it is not classically associated with gastrointestinal c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American College of Gastroenterology
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772063/ https://www.ncbi.nlm.nih.gov/pubmed/29392152 http://dx.doi.org/10.14309/crj.2018.5 |
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author | Robey, Benjamin S. Peery, Anne F. Dellon, Evan S. |
author_facet | Robey, Benjamin S. Peery, Anne F. Dellon, Evan S. |
author_sort | Robey, Benjamin S. |
collection | PubMed |
description | Marfan syndrome is an autosomal dominant disorder involving mutation in the FBN1 gene, which encodes fibrillin-1, a protein critical to maintain the integrity of connective tissue. A mutation in this gene can affect multiple organ systems, but it is not classically associated with gastrointestinal complications. We describe a man with Marfan syndrome with multiple small bowel diverticula leading to small intestinal bacterial overgrowth and recurrent small bowel perforations. |
format | Online Article Text |
id | pubmed-5772063 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | American College of Gastroenterology |
record_format | MEDLINE/PubMed |
spelling | pubmed-57720632018-02-01 Small Bowel Diverticulosis and Jejunal Perforation in Marfan Syndrome Robey, Benjamin S. Peery, Anne F. Dellon, Evan S. ACG Case Rep J Case Report Marfan syndrome is an autosomal dominant disorder involving mutation in the FBN1 gene, which encodes fibrillin-1, a protein critical to maintain the integrity of connective tissue. A mutation in this gene can affect multiple organ systems, but it is not classically associated with gastrointestinal complications. We describe a man with Marfan syndrome with multiple small bowel diverticula leading to small intestinal bacterial overgrowth and recurrent small bowel perforations. American College of Gastroenterology 2018-01-17 /pmc/articles/PMC5772063/ /pubmed/29392152 http://dx.doi.org/10.14309/crj.2018.5 Text en Copyright © Robey et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/ |
spellingShingle | Case Report Robey, Benjamin S. Peery, Anne F. Dellon, Evan S. Small Bowel Diverticulosis and Jejunal Perforation in Marfan Syndrome |
title | Small Bowel Diverticulosis and Jejunal Perforation in Marfan Syndrome |
title_full | Small Bowel Diverticulosis and Jejunal Perforation in Marfan Syndrome |
title_fullStr | Small Bowel Diverticulosis and Jejunal Perforation in Marfan Syndrome |
title_full_unstemmed | Small Bowel Diverticulosis and Jejunal Perforation in Marfan Syndrome |
title_short | Small Bowel Diverticulosis and Jejunal Perforation in Marfan Syndrome |
title_sort | small bowel diverticulosis and jejunal perforation in marfan syndrome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772063/ https://www.ncbi.nlm.nih.gov/pubmed/29392152 http://dx.doi.org/10.14309/crj.2018.5 |
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