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Antireflux Status Post Roux-en-Y anastomosis: An Experimental Study for Optimal Antireflux Technique

BACKGROUND: Roux-en-Y hepaticojejunostomy has been a gold standard to establish biliary-enteric anastomosis for various surgical indications, but associated with variable incidences of cholangitis. This experimental study was conducted to report a modification in Roux-en-Y anastomosis for possible b...

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Autores principales: Verma, Ajay Kumar, Purbey, Om Prakash, Kureel, Shiv Narain, Gupta, Archika, Pandey, Anand, Sunil, Kanoujia, Chaubey, Digamber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772092/
https://www.ncbi.nlm.nih.gov/pubmed/29386762
http://dx.doi.org/10.4103/jiaps.JIAPS_75_17
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author Verma, Ajay Kumar
Purbey, Om Prakash
Kureel, Shiv Narain
Gupta, Archika
Pandey, Anand
Sunil, Kanoujia
Chaubey, Digamber
author_facet Verma, Ajay Kumar
Purbey, Om Prakash
Kureel, Shiv Narain
Gupta, Archika
Pandey, Anand
Sunil, Kanoujia
Chaubey, Digamber
author_sort Verma, Ajay Kumar
collection PubMed
description BACKGROUND: Roux-en-Y hepaticojejunostomy has been a gold standard to establish biliary-enteric anastomosis for various surgical indications, but associated with variable incidences of cholangitis. This experimental study was conducted to report a modification in Roux-en-Y anastomosis for possible better alternative to provide antireflux procedure after Roux-en-Y biliary-enteric anastomosis with the aim to minimize the possibility of reflux and its consequences. MATERIALS AND METHODS: For experimental study, the required fresh segment of Lamb's small intestine was procured. Three sets of Roux-en-Y anastomosis were created for each experiment. In set 1, there was simple Roux-en-Y anastomosis. In set 2, Roux-en-Y anastomosis along with 4–5 cm long spur between the hepatic and duodenal limbs was created. In set 3, in addition to Roux-en-Y with creation of spur, additional antireflux mechanism was created at the junction of upper two-third and lower one-third of the hepatic limb. Saline mixed contrast was infused by infusion pump to raise the intraluminal pressure to more than 10 cm of H(2)O. X-ray was taken at that time. RESULTS: In set 1, all preparations demonstrated reflux of contrast in the hepatic limb. The set 2 also demonstrated the same findings of 100% reflux in the hepatic limb. In set 3, No reflux was observed in 8 (80%) preparations while remaining 2 (20%) preparations reveal partial reflux. CONCLUSION: This experimental study suggests that the provision of spur and additional valve may be able to decrease the possibility of reflux in Roux-en-Y biliary-enteric anastomosis.
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spelling pubmed-57720922018-01-31 Antireflux Status Post Roux-en-Y anastomosis: An Experimental Study for Optimal Antireflux Technique Verma, Ajay Kumar Purbey, Om Prakash Kureel, Shiv Narain Gupta, Archika Pandey, Anand Sunil, Kanoujia Chaubey, Digamber J Indian Assoc Pediatr Surg Original Article BACKGROUND: Roux-en-Y hepaticojejunostomy has been a gold standard to establish biliary-enteric anastomosis for various surgical indications, but associated with variable incidences of cholangitis. This experimental study was conducted to report a modification in Roux-en-Y anastomosis for possible better alternative to provide antireflux procedure after Roux-en-Y biliary-enteric anastomosis with the aim to minimize the possibility of reflux and its consequences. MATERIALS AND METHODS: For experimental study, the required fresh segment of Lamb's small intestine was procured. Three sets of Roux-en-Y anastomosis were created for each experiment. In set 1, there was simple Roux-en-Y anastomosis. In set 2, Roux-en-Y anastomosis along with 4–5 cm long spur between the hepatic and duodenal limbs was created. In set 3, in addition to Roux-en-Y with creation of spur, additional antireflux mechanism was created at the junction of upper two-third and lower one-third of the hepatic limb. Saline mixed contrast was infused by infusion pump to raise the intraluminal pressure to more than 10 cm of H(2)O. X-ray was taken at that time. RESULTS: In set 1, all preparations demonstrated reflux of contrast in the hepatic limb. The set 2 also demonstrated the same findings of 100% reflux in the hepatic limb. In set 3, No reflux was observed in 8 (80%) preparations while remaining 2 (20%) preparations reveal partial reflux. CONCLUSION: This experimental study suggests that the provision of spur and additional valve may be able to decrease the possibility of reflux in Roux-en-Y biliary-enteric anastomosis. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5772092/ /pubmed/29386762 http://dx.doi.org/10.4103/jiaps.JIAPS_75_17 Text en Copyright: © 2017 Journal of Indian Association of Pediatric Surgeons http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Verma, Ajay Kumar
Purbey, Om Prakash
Kureel, Shiv Narain
Gupta, Archika
Pandey, Anand
Sunil, Kanoujia
Chaubey, Digamber
Antireflux Status Post Roux-en-Y anastomosis: An Experimental Study for Optimal Antireflux Technique
title Antireflux Status Post Roux-en-Y anastomosis: An Experimental Study for Optimal Antireflux Technique
title_full Antireflux Status Post Roux-en-Y anastomosis: An Experimental Study for Optimal Antireflux Technique
title_fullStr Antireflux Status Post Roux-en-Y anastomosis: An Experimental Study for Optimal Antireflux Technique
title_full_unstemmed Antireflux Status Post Roux-en-Y anastomosis: An Experimental Study for Optimal Antireflux Technique
title_short Antireflux Status Post Roux-en-Y anastomosis: An Experimental Study for Optimal Antireflux Technique
title_sort antireflux status post roux-en-y anastomosis: an experimental study for optimal antireflux technique
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772092/
https://www.ncbi.nlm.nih.gov/pubmed/29386762
http://dx.doi.org/10.4103/jiaps.JIAPS_75_17
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