Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation

Group 3 innate lymphoid cells (ILC3s) sense environmental signals and are critical for tissue integrity in the intestine. Yet, which signals are sensed and what receptors control ILC3 function remain poorly understood. Here, we show that ILC3s with a lymphoid-tissue-inducer (LTi) phenotype expressed...

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Detalles Bibliográficos
Autores principales: Emgård, Johanna, Kammoun, Hana, García-Cassani, Bethania, Chesné, Julie, Parigi, Sara M., Jacob, Jean-Marie, Cheng, Hung-Wei, Evren, Elza, Das, Srustidhar, Czarnewski, Paulo, Sleiers, Natalie, Melo-Gonzalez, Felipe, Kvedaraite, Egle, Svensson, Mattias, Scandella, Elke, Hepworth, Matthew R., Huber, Samuel, Ludewig, Burkhard, Peduto, Lucie, Villablanca, Eduardo J., Veiga-Fernandes, Henrique, Pereira, João P., Flavell, Richard A., Willinger, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772175/
https://www.ncbi.nlm.nih.gov/pubmed/29343433
http://dx.doi.org/10.1016/j.immuni.2017.11.020

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