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The Swinholide Biosynthesis Gene Cluster from a Terrestrial Cyanobacterium, Nostoc sp. Strain UHCC 0450

Swinholides are 42-carbon ring polyketides with a 2-fold axis of symmetry. They are potent cytotoxins that disrupt the actin cytoskeleton. Swinholides were discovered from the marine sponge Theonella sp. and were long suspected to be produced by symbiotic bacteria. Misakinolide, a structural variant...

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Detalles Bibliográficos
Autores principales:	Humisto, Anu, Jokela, Jouni, Liu, Liwei, Wahlsten, Matti, Wang, Hao, Permi, Perttu, Machado, João Paulo, Antunes, Agostinho, Fewer, David P., Sivonen, Kaarina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Environmental Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772238/ https://www.ncbi.nlm.nih.gov/pubmed/29150506 http://dx.doi.org/10.1128/AEM.02321-17

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