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Pharmacological targeting of BET proteins attenuates radiation-induced lung fibrosis

Radiation-induced lung injury has restricted radiotherapy for thoracic cancer. The purpose of this study was to investigate the radioprotective effects of bromodomain and extra terminal (BET) inhibitor JQ1 in a murine model of pulmonary damage. Chest computed tomography (CT) was performed in a rat m...

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Detalles Bibliográficos
Autores principales:	Wang, Jian, Zhou, Fangzheng, Li, Zhenyu, Mei, Hong, Wang, Ye, Ma, Hong, Shi, Liangliang, Huang, Ai, Zhang, Tao, Lin, Zhenyu, Wu, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772369/ https://www.ncbi.nlm.nih.gov/pubmed/29343723 http://dx.doi.org/10.1038/s41598-018-19343-9

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