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Antibacterial effect evaluation of moxalactam against extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae with in vitro pharmacokinetics/pharmacodynamics simulation

OBJECTIVES: The aim of this study was to evaluate the bactericidal effects of moxalactam (MOX), cefotaxime (CTX), and cefoperazone/sulbactam (CFZ/SBT) against extended-spectrum β-lactamase (ESBL) producing Escherichia coli and Klebsiella pneumoniae, using an in vitro pharmacokinetics (PK)/pharmacody...

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Detalles Bibliográficos
Autores principales: Huang, Chen, Zheng, Beiwen, Yu, Wei, Niu, Tianshui, Xiao, Tingting, Zhang, Jing, Xiao, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772397/
https://www.ncbi.nlm.nih.gov/pubmed/29391816
http://dx.doi.org/10.2147/IDR.S150431