Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease

Hypoxia-inducible factors (HIFs) are key elements for controlling immune cell metabolism and functions. While HIFs are known to be involved in T cells and macrophages activation, their functions in B lymphocytes are poorly defined. Here, we show that hypoxia-inducible factor-1α (HIF-1α) contributes...

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Detalles Bibliográficos
Autores principales: Meng, Xianyi, Grötsch, Bettina, Luo, Yubin, Knaup, Karl Xaver, Wiesener, Michael Sean, Chen, Xiao-Xiang, Jantsch, Jonathan, Fillatreau, Simon, Schett, Georg, Bozec, Aline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772476/
https://www.ncbi.nlm.nih.gov/pubmed/29343683
http://dx.doi.org/10.1038/s41467-017-02683-x

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