Cargando…

MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A

Mucosal-associated invariant T (MAIT) cells are innate-like T cells that can detect bacteria-derived metabolites presented on MR1. Here we show, using a controlled infection of humans with live Salmonella enterica serovar Paratyphi A, that MAIT cells are activated during infection, an effect maintai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Howson, Lauren J., Napolitani, Giorgio, Shepherd, Dawn, Ghadbane, Hemza, Kurupati, Prathiba, Preciado-Llanes, Lorena, Rei, Margarida, Dobinson, Hazel C., Gibani, Malick M., Teng, Karen Wei Weng, Newell, Evan W., Veerapen, Natacha, Besra, Gurdyal S., Pollard, Andrew J., Cerundolo, Vincenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772558/ https://www.ncbi.nlm.nih.gov/pubmed/29343684 http://dx.doi.org/10.1038/s41467-017-02540-x

Ejemplares similares

Amide Analogues of CD1d Agonists Modulate iNKT-Cell-Mediated Cytokine Production
por: Wojno, Justyna, et al.
Publicado: (2012)

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease
por: Preciado-Llanes, Lorena, et al.
Publicado: (2020)

Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues
por: Jervis, Peter J., et al.
Publicado: (2012)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation
por: Veerapen, Natacha, et al.
Publicado: (2011)

Non‐glycosidic compounds can stimulate both human and mouse iNKT cells
por: Jukes, John‐Paul, et al.
Publicado: (2016)

Homologous and heterologous re-challenge with Salmonella Typhi and Salmonella Paratyphi A in a randomised controlled human infection model
por: Gibani, Malick M., et al.
Publicado: (2020)

Development and Evaluation of a Blood Culture PCR Assay for Rapid Detection of Salmonella Paratyphi A in Clinical Samples
por: Zhou, Liqing, et al.
Publicado: (2016)

Design, Synthesis, and Functional Activity of Labeled CD1d Glycolipid Agonists
por: Jervis, Peter J., et al.
Publicado: (2013)

Correction: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells
por: Jimeno, Rebeca, et al.
Publicado: (2020)

Synthesis and biological activity of α-galactosyl ceramide KRN7000 and galactosyl (α1→2) galactosyl ceramide
por: Veerapen, Natacha, et al.
Publicado: (2009)

Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells
por: Jimeno, Rebeca, et al.
Publicado: (2019)

The C-Terminal Domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC Is a Lectin-Like Carbohydrate Binding Module
por: Alderwick, Luke J., et al.
Publicado: (2011)

Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells
por: Salio, Mariolina, et al.
Publicado: (2017)

Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg(2+)
por: Brown, Alistair K, et al.
Publicado: (2007)

Calreticulin Controls the Rate of Assembly of CD1d Molecules in the Endoplasmic Reticulum
por: Zhu, Yajuan, et al.
Publicado: (2010)

Synthesis and biological activity of α-l-fucosyl ceramides, analogues of the potent agonist, α-d-galactosyl ceramide KRN7000
por: Veerapen, Natacha, et al.
Publicado: (2010)

Biased MAIT TCR Usage Poised for Limited Antigen Diversity?
por: Souter, Michael N. T., et al.
Publicado: (2020)

The Impact of Vaccination and Prior Exposure on Stool Shedding of Salmonella Typhi and Salmonella Paratyphi in 6 Controlled Human Infection Studies
por: Gibani, Malick M, et al.
Publicado: (2019)

Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan
por: Jankute, Monika, et al.
Publicado: (2016)

DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid
por: Abrahams, Katherine A., et al.
Publicado: (2023)

Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model
por: Dobinson, Hazel C., et al.
Publicado: (2017)

Synthesis and biological activity of α-glucosyl C24:0 and C20:2 ceramides
por: Jervis, Peter J., et al.
Publicado: (2010)

Endoplasmic Reticulum Glycoprotein Quality Control Regulates CD1d Assembly and CD1d-mediated Antigen Presentation
por: Kunte, Amit, et al.
Publicado: (2013)

Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone
por: Muppidi, Jagan R., et al.
Publicado: (2011)

Expansion of donor-unrestricted MAIT cells with enhanced cytolytic function suitable for TCR redirection
por: Parrot, Tiphaine, et al.
Publicado: (2021)

Acceptor Substrate Discrimination in Phosphatidyl-myo-inositol Mannoside Synthesis: STRUCTURAL AND MUTATIONAL ANALYSIS OF MANNOSYLTRANSFERASE CORYNEBACTERIUM GLUTAMICUM PimB′
por: Batt, Sarah M., et al.
Publicado: (2010)

A humanized mouse model for in vivo evaluation of invariant Natural Killer T cell responses
por: Saavedra-Avila, Noemi Alejandra, et al.
Publicado: (2022)

The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation
por: Kulicke, Corinna A., et al.
Publicado: (2021)

MKAN27435 Is Required for the Biosynthesis of Higher Subclasses of Lipooligosaccharides in Mycobacterium kansasii
por: Nataraj, Vijayashankar, et al.
Publicado: (2015)

The hydrolase LpqI primes mycobacterial peptidoglycan recycling
por: Moynihan, Patrick J., et al.
Publicado: (2019)

Ligand-dependent downregulation of MR1 cell surface expression
por: Salio, Mariolina, et al.
Publicado: (2020)

TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions
por: Leng, Tianqi, et al.
Publicado: (2019)

Immunophenotypic characterization of TCR γδ T cells and MAIT cells in HIV-infected individuals developing Hodgkin’s lymphoma
por: Muller, Christina K. S., et al.
Publicado: (2021)

Characterization of the TCRβ repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients
por: Jirouš Drulak, Maja, et al.
Publicado: (2023)

Psoriasis and the MAITing game: A role for IL-17A+ invariant TCR CD8+ T cells in psoriasis?
por: Johnston, Andrew, et al.
Publicado: (2014)

Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b
por: Garg, Salil, et al.
Publicado: (2011)

Salmonella Paratyphi Neck Abscess
por: Behera, Bijayini, et al.
Publicado: (2012)

MAIT cells and viruses
por: Ussher, James E, et al.
Publicado: (2018)

MAIT cells and the microbiome
por: Jabeen, Maisha F., et al.
Publicado: (2023)

MicroRNA-155 Regulates MAIT1 and MAIT17 Cell Differentiation
por: Liu, Tingting, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_u7u892l26vfmatdci0dlt5dd7b