Angiotensin II Overstimulation Leads to an Increased Susceptibility to Dilated Cardiomyopathy and Higher Mortality in Female Mice

Heart failure (HF) is associated with high mortality and affects men and women differently. The underlying mechanisms for these sex-related differences remain largely unexplored. Accordingly, using mice with cardiac-specific overexpression of the angiotensin II (ANGII) type 1 receptor (AT1R), we exp...

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Detalles Bibliográficos
Autores principales: Mathieu, Sophie, El Khoury, Nabil, Rivard, Katy, Paradis, Pierre, Nemer, Mona, Fiset, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772611/
https://www.ncbi.nlm.nih.gov/pubmed/29343862
http://dx.doi.org/10.1038/s41598-018-19436-5

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