Incorporation of iloprost in phospholipase-resistant phospholipid scaffold enhances its barrier protective effects on pulmonary endothelium

Correction of barrier dysfunction and inflammation in acute lung injury (ALI) represents an important problem. Previous studies demonstrate barrier-protective and anti-inflammatory effects of bioactive lipid prostacyclin and its stable analog iloprost (ILO). We generated a phospholipase resistant sy...

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Detalles Bibliográficos
Autores principales: Oskolkova, Olga, Sarich, Nicolene, Tian, Yufeng, Gawlak, Grzegorz, Meng, Fanyong, Bochkov, Valery N., Berdyshev, Evgeny, Birukova, Anna A., Birukov, Konstantin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772615/
https://www.ncbi.nlm.nih.gov/pubmed/29343759
http://dx.doi.org/10.1038/s41598-018-19197-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772615/
https://www.ncbi.nlm.nih.gov/pubmed/29343759
http://dx.doi.org/10.1038/s41598-018-19197-1

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