A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly

NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed pain medications. It is a highly effective drug class for pain and inflammation; however, NSAIDs are known for multiple adverse effects, including gastrointestinal bleeding, cardiovascular side effects, and NSAID...

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Autores principales: Wongrakpanich, Supakanya, Wongrakpanich, Amaraporn, Melhado, Katie, Rangaswami, Janani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772852/
https://www.ncbi.nlm.nih.gov/pubmed/29392089
http://dx.doi.org/10.14336/AD.2017.0306
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author Wongrakpanich, Supakanya
Wongrakpanich, Amaraporn
Melhado, Katie
Rangaswami, Janani
author_facet Wongrakpanich, Supakanya
Wongrakpanich, Amaraporn
Melhado, Katie
Rangaswami, Janani
author_sort Wongrakpanich, Supakanya
collection PubMed
description NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed pain medications. It is a highly effective drug class for pain and inflammation; however, NSAIDs are known for multiple adverse effects, including gastrointestinal bleeding, cardiovascular side effects, and NSAID induced nephrotoxicity. As our society ages, it is crucial to have comprehensive knowledge of this class of medication in the elderly population. Therefore, we reviewed the pharmacodynamics and pharmacokinetics, current guidelines for NSAIDs use, adverse effect profile, and drug interaction of NSAIDs and commonly used medications in the elderly.
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spelling pubmed-57728522018-02-02 A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly Wongrakpanich, Supakanya Wongrakpanich, Amaraporn Melhado, Katie Rangaswami, Janani Aging Dis Review NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed pain medications. It is a highly effective drug class for pain and inflammation; however, NSAIDs are known for multiple adverse effects, including gastrointestinal bleeding, cardiovascular side effects, and NSAID induced nephrotoxicity. As our society ages, it is crucial to have comprehensive knowledge of this class of medication in the elderly population. Therefore, we reviewed the pharmacodynamics and pharmacokinetics, current guidelines for NSAIDs use, adverse effect profile, and drug interaction of NSAIDs and commonly used medications in the elderly. JKL International LLC 2018-02-01 /pmc/articles/PMC5772852/ /pubmed/29392089 http://dx.doi.org/10.14336/AD.2017.0306 Text en Copyright: © 2017 Wongrakpanich et al. http://creativecommons.org/licenses/by/2.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Review
Wongrakpanich, Supakanya
Wongrakpanich, Amaraporn
Melhado, Katie
Rangaswami, Janani
A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly
title A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly
title_full A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly
title_fullStr A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly
title_full_unstemmed A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly
title_short A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly
title_sort comprehensive review of non-steroidal anti-inflammatory drug use in the elderly
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772852/
https://www.ncbi.nlm.nih.gov/pubmed/29392089
http://dx.doi.org/10.14336/AD.2017.0306
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