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Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults

There has been increasing interest and research into sarcopenia in community-dwelling older adults since the European Working Group on Sarcopenia in Older People (EWGSOP) agreed a consensus definition in 2010. Sarcopenia has been defined as loss of muscle mass with loss of muscle function (strength...

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Autores principales: Welch, Carly, K. Hassan-Smith, Zaki, A. Greig, Carolyn, M. Lord, Janet, A. Jackson, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772853/
https://www.ncbi.nlm.nih.gov/pubmed/29392090
http://dx.doi.org/10.14336/AD.2017.0315
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author Welch, Carly
K. Hassan-Smith, Zaki
A. Greig, Carolyn
M. Lord, Janet
A. Jackson, Thomas
author_facet Welch, Carly
K. Hassan-Smith, Zaki
A. Greig, Carolyn
M. Lord, Janet
A. Jackson, Thomas
author_sort Welch, Carly
collection PubMed
description There has been increasing interest and research into sarcopenia in community-dwelling older adults since the European Working Group on Sarcopenia in Older People (EWGSOP) agreed a consensus definition in 2010. Sarcopenia has been defined as loss of muscle mass with loss of muscle function (strength or physical performance), with measurements two Standard Deviations (SDs) below the mean of a young reference population. This definition does not necessitate longitudinal measurements, or the absence of acute illness and diagnosis can be made from single measurements. We hypothesise that hospitalisation, due to a combination of acute inflammatory burden and muscle disuse, leads to an acute decline in muscle mass and function and may lead to some individuals meeting criteria for sarcopenia, acutely, based on the EWGSOP definition. This may be partially recoverable or may lead to increased risk of developing sarcopenia long-term. We have denoted the term “acute sarcopenia” to refer to acute loss of muscle mass and function associated with hospitalisation. This review discusses some of the current available research in this context and also identifies some of the knowledge gaps and potential areas for future research.
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spelling pubmed-57728532018-02-02 Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults Welch, Carly K. Hassan-Smith, Zaki A. Greig, Carolyn M. Lord, Janet A. Jackson, Thomas Aging Dis Review There has been increasing interest and research into sarcopenia in community-dwelling older adults since the European Working Group on Sarcopenia in Older People (EWGSOP) agreed a consensus definition in 2010. Sarcopenia has been defined as loss of muscle mass with loss of muscle function (strength or physical performance), with measurements two Standard Deviations (SDs) below the mean of a young reference population. This definition does not necessitate longitudinal measurements, or the absence of acute illness and diagnosis can be made from single measurements. We hypothesise that hospitalisation, due to a combination of acute inflammatory burden and muscle disuse, leads to an acute decline in muscle mass and function and may lead to some individuals meeting criteria for sarcopenia, acutely, based on the EWGSOP definition. This may be partially recoverable or may lead to increased risk of developing sarcopenia long-term. We have denoted the term “acute sarcopenia” to refer to acute loss of muscle mass and function associated with hospitalisation. This review discusses some of the current available research in this context and also identifies some of the knowledge gaps and potential areas for future research. JKL International LLC 2018-02-01 /pmc/articles/PMC5772853/ /pubmed/29392090 http://dx.doi.org/10.14336/AD.2017.0315 Text en Copyright: © 2017 Welch et al. http://creativecommons.org/licenses/by/2.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Review
Welch, Carly
K. Hassan-Smith, Zaki
A. Greig, Carolyn
M. Lord, Janet
A. Jackson, Thomas
Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults
title Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults
title_full Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults
title_fullStr Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults
title_full_unstemmed Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults
title_short Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults
title_sort acute sarcopenia secondary to hospitalisation - an emerging condition affecting older adults
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772853/
https://www.ncbi.nlm.nih.gov/pubmed/29392090
http://dx.doi.org/10.14336/AD.2017.0315
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