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Identification of pain categories associated with change in pain in patients receiving placebo: data from two phase 3 randomized clinical trials in symptomatic knee osteoarthritis
BACKGROUND: Pain is the principal clinical symptom of osteoarthritis (OA), and development of safe and effective analgesics for OA pain is needed. Drug development of new analgesics for OA pain is impaired by substantial change in pain in patients receiving placebo, and more data describing clinical...
Autores principales: | Bihlet, Asger Reinstrup, Byrjalsen, Inger, Bay-Jensen, Anne-Christine, Andersen, Jeppe Ragnar, Christiansen, Claus, Riis, Bente Juel, Valter, Ivo, Karsdal, Morten A., Hochberg, Marc C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773024/ https://www.ncbi.nlm.nih.gov/pubmed/29343266 http://dx.doi.org/10.1186/s12891-018-1938-5 |
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