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INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia
BACKGROUND: Acute myeloid leukemia (AML) with mutated nucleophosmin (NPM1) has been recognized as a distinct leukemia entity in the 2016 World Health Organization (WHO) classification. The genetic events underlying oncogenesis in NPM1-mutated AML that is characterized by a normal karyotype remain un...
Autores principales: | Jin, Hongjun, Yang, Liyuan, Wang, Lu, Yang, Zailin, Zhan, Qian, Tao, Yao, Zou, Qin, Tang, Yuting, Xian, Jingrong, Zhang, Shuaishuai, Jing, Yipei, Zhang, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773044/ https://www.ncbi.nlm.nih.gov/pubmed/29343273 http://dx.doi.org/10.1186/s13046-018-0675-9 |
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