The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury

BACKGROUND: We previously showed that increased asymmetric dimethylarginine (ADMA) biliary excretion occurs during hepatic ischemia/reperfusion (I/R), prompting us to study the effects of the farnesoid X receptor (FXR) agonist obeticholic acid (OCA) on bile, serum and tissue levels of ADMA after I/R...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferrigno, Andrea, Di Pasqua, Laura Giuseppina, Berardo, Clarissa, Siciliano, Veronica, Rizzo, Vittoria, Adorini, Luciano, Richelmi, Plinio, Vairetti, Mariapia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773219/
https://www.ncbi.nlm.nih.gov/pubmed/29346429
http://dx.doi.org/10.1371/journal.pone.0191430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773219/
https://www.ncbi.nlm.nih.gov/pubmed/29346429
http://dx.doi.org/10.1371/journal.pone.0191430

Ejemplares similares