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Higher sequence diversity in the vaginal tract than in blood at early HIV-1 infection
In the majority of cases, human immunodeficiency virus type 1 (HIV-1) infection is transmitted through sexual intercourse. A single founder virus in the blood of the newly infected donor emerges from a genetic bottleneck, while in rarer instances multiple viruses are responsible for systemic infecti...
Autores principales: | Klein, Katja, Nickel, Gabrielle, Nankya, Immaculate, Kyeyune, Fred, Demers, Korey, Ndashimye, Emmanuel, Kwok, Cynthia, Chen, Pai-Lien, Rwambuya, Sandra, Poon, Art, Munjoma, Marshall, Chipato, Tsungai, Byamugisha, Josaphat, Mugyenyi, Peter, Salata, Robert A., Morrison, Charles S., Arts, Eric J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773221/ https://www.ncbi.nlm.nih.gov/pubmed/29346424 http://dx.doi.org/10.1371/journal.ppat.1006754 |
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