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Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs

Rapid antigenic evolution enables the persistence of seasonal influenza A and B viruses in human populations despite widespread herd immunity. Understanding viral mechanisms that enable antigenic evolution is critical for designing durable vaccines and therapeutics. Here, we utilize the primerID met...

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Detalles Bibliográficos
Autores principales: Kosik, Ivan, Ince, William L., Gentles, Lauren E., Oler, Andrew J., Kosikova, Martina, Angel, Matthew, Magadán, Javier G., Xie, Hang, Brooke, Christopher B., Yewdell, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773227/
https://www.ncbi.nlm.nih.gov/pubmed/29346435
http://dx.doi.org/10.1371/journal.ppat.1006796

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