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Decrement of Serum Vitamin D Level After Stroke
OBJECTIVE: To investigate the serum vitamin D level and its determinant factors in stroke patients. METHODS: Fifty-one stroke patients who had documented serum level of 25-hydroxyvitamin D(25(OH)D) were included. Patients were divided into subacute (n=23) and chronic groups (n=28). The mean levels o...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Academy of Rehabilitation Medicine
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773437/ https://www.ncbi.nlm.nih.gov/pubmed/29354570 http://dx.doi.org/10.5535/arm.2017.41.6.944 |
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author | Kim, Kiyoung Cho, Kye Hee Im, Sang Hee Choi, Jaewoo Yu, Junghoon Kim, MinYoung |
author_facet | Kim, Kiyoung Cho, Kye Hee Im, Sang Hee Choi, Jaewoo Yu, Junghoon Kim, MinYoung |
author_sort | Kim, Kiyoung |
collection | PubMed |
description | OBJECTIVE: To investigate the serum vitamin D level and its determinant factors in stroke patients. METHODS: Fifty-one stroke patients who had documented serum level of 25-hydroxyvitamin D(25(OH)D) were included. Patients were divided into subacute (n=23) and chronic groups (n=28). The mean levels of 25(OH)D of the two groups were compared. Correlations between each 25(OH)D level and post-stroke duration were also analyzed. To assess other possible influencing factors, patients were subdivided by ambulation ability and feeding methods for comparison of 25(OH)D level. RESULTS: The mean level of 25(OH)D was significantly lower in the chronic group than in the subacute group (12.3 vs. 16.3 ng/mL; p<0.05). The serum 25(OH)D level decreased according to the duration after stroke (r=−0.52, p=0.01). Patients with a history of total parenteral nutrition had lower 25(OH)D levels than subjects who had enteral nutrition in the subacute group (7.3 vs. 18.8 ng/mL; p<0.01). However, the levels of 25(OH)D were not different between the oral feeding and tube feeding groups. Among the chronic group subjects, patients who could walk without assistance had higher 25(OH)D levels than non-ambulatory patients (ambulatory vs. non-ambulatory group; 18.3 vs. 11.3 ng/mL; p<0.05). CONCLUSION: After stroke onset, serum vitamin D level decreases with time regardless of feeding methods, and total parenteral nutrition may aggravate its deficiency. In terms of long-term care, non-ambulatory patients might be at a higher risk of vitamin D deficiency. Supplementation of vitamin D should be considered especially for stroke patients who are non-ambulatory and on total parenteral nutrition. |
format | Online Article Text |
id | pubmed-5773437 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Korean Academy of Rehabilitation Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-57734372018-01-21 Decrement of Serum Vitamin D Level After Stroke Kim, Kiyoung Cho, Kye Hee Im, Sang Hee Choi, Jaewoo Yu, Junghoon Kim, MinYoung Ann Rehabil Med Original Article OBJECTIVE: To investigate the serum vitamin D level and its determinant factors in stroke patients. METHODS: Fifty-one stroke patients who had documented serum level of 25-hydroxyvitamin D(25(OH)D) were included. Patients were divided into subacute (n=23) and chronic groups (n=28). The mean levels of 25(OH)D of the two groups were compared. Correlations between each 25(OH)D level and post-stroke duration were also analyzed. To assess other possible influencing factors, patients were subdivided by ambulation ability and feeding methods for comparison of 25(OH)D level. RESULTS: The mean level of 25(OH)D was significantly lower in the chronic group than in the subacute group (12.3 vs. 16.3 ng/mL; p<0.05). The serum 25(OH)D level decreased according to the duration after stroke (r=−0.52, p=0.01). Patients with a history of total parenteral nutrition had lower 25(OH)D levels than subjects who had enteral nutrition in the subacute group (7.3 vs. 18.8 ng/mL; p<0.01). However, the levels of 25(OH)D were not different between the oral feeding and tube feeding groups. Among the chronic group subjects, patients who could walk without assistance had higher 25(OH)D levels than non-ambulatory patients (ambulatory vs. non-ambulatory group; 18.3 vs. 11.3 ng/mL; p<0.05). CONCLUSION: After stroke onset, serum vitamin D level decreases with time regardless of feeding methods, and total parenteral nutrition may aggravate its deficiency. In terms of long-term care, non-ambulatory patients might be at a higher risk of vitamin D deficiency. Supplementation of vitamin D should be considered especially for stroke patients who are non-ambulatory and on total parenteral nutrition. Korean Academy of Rehabilitation Medicine 2017-12 2017-12-28 /pmc/articles/PMC5773437/ /pubmed/29354570 http://dx.doi.org/10.5535/arm.2017.41.6.944 Text en Copyright © 2017 by Korean Academy of Rehabilitation Medicine http://creativecommons.org/licenses/by-nc/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Kiyoung Cho, Kye Hee Im, Sang Hee Choi, Jaewoo Yu, Junghoon Kim, MinYoung Decrement of Serum Vitamin D Level After Stroke |
title | Decrement of Serum Vitamin D Level After Stroke |
title_full | Decrement of Serum Vitamin D Level After Stroke |
title_fullStr | Decrement of Serum Vitamin D Level After Stroke |
title_full_unstemmed | Decrement of Serum Vitamin D Level After Stroke |
title_short | Decrement of Serum Vitamin D Level After Stroke |
title_sort | decrement of serum vitamin d level after stroke |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773437/ https://www.ncbi.nlm.nih.gov/pubmed/29354570 http://dx.doi.org/10.5535/arm.2017.41.6.944 |
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