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Structural basis of SALM5-induced PTPδ dimerization for synaptic differentiation

SALM5, a synaptic adhesion molecule implicated in autism, induces presynaptic differentiation through binding to the LAR family receptor protein tyrosine phosphatases (LAR-RPTPs) that have been highlighted as presynaptic hubs for synapse formation. The mechanisms underlying SALM5/LAR-RPTP interactio...

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Detalles Bibliográficos
Autores principales:	Lin, Zhaohan, Liu, Jianmei, Ding, Huandi, Xu, Fei, Liu, Heli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773555/ https://www.ncbi.nlm.nih.gov/pubmed/29348579 http://dx.doi.org/10.1038/s41467-017-02414-2

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