Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements

Arsenic is one of the most important human carcinogens and environmental pollutants. However, the evaluation of the underlying carcinogenic mechanisms is challenging due to the lack of suitable in vivo and in vitro models, as distinct interspecies differences in arsenic metabolism exist. Thus, it is...

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Detalles Bibliográficos
Autores principales: Weinmuellner, R., Kryeziu, K., Zbiral, B., Tav, K., Schoenhacker-Alte, B., Groza, D., Wimmer, L., Schosserer, M., Nagelreiter, F., Rösinger, S., Mildner, M., Tschachler, E., Grusch, M., Grillari, J., Heffeter, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Inorganic Compounds
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773649/
https://www.ncbi.nlm.nih.gov/pubmed/28776197
http://dx.doi.org/10.1007/s00204-017-2034-6

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