Cargando…
An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition
Epidemiological studies have observed an association between pesticide exposure and the development of Parkinson’s disease, but have not established causality. The concept of an adverse outcome pathway (AOP) has been developed as a framework for the organization of available information linking the...
Autores principales: | Terron, Andrea, Bal-Price, Anna, Paini, Alicia, Monnet-Tschudi, Florianne, Bennekou, Susanne Hougaard, Leist, Marcel, Schildknecht, Stefan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773657/ https://www.ncbi.nlm.nih.gov/pubmed/29209747 http://dx.doi.org/10.1007/s00204-017-2133-4 |
Ejemplares similares
-
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes
por: Fritsche, Ellen, et al.
Publicado: (2018) -
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes
por: Bal-Price, Anna, et al.
Publicado: (2015) -
Preferential Extracellular Generation of the Active Parkinsonian Toxin MPP(+) by Transporter-Independent Export of the Intermediate MPDP(+)
por: Schildknecht, Stefan, et al.
Publicado: (2015) -
Moving towards a holistic approach for human health risk assessment – Is the current approach fit for purpose?
por: Bennekou, Susanne Hougaard
Publicado: (2019) -
Transcriptional landscape of mitochondrial electron transport chain inhibition in renal cells
por: Carta, Giada, et al.
Publicado: (2023)