Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness

Although a growing body of evidence indicates that phenotypic plasticity exhibited by glioblastoma cells plays a central role in tumor development and post-therapy recurrence, the master drivers of their aggressiveness remain elusive. Here we mapped the changes in active (H3K4me3) and repressive (H3...

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Detalles Bibliográficos
Autores principales: Bogeas, Alexandra, Morvan-Dubois, Ghislaine, El-Habr, Elias A., Lejeune, François-Xavier, Defrance, Matthieu, Narayanan, Ashwin, Kuranda, Klaudia, Burel-Vandenbos, Fanny, Sayd, Salwa, Delaunay, Virgile, Dubois, Luiz G., Parrinello, Hugues, Rialle, Stéphanie, Fabrega, Sylvie, Idbaih, Ahmed, Haiech, Jacques, Bièche, Ivan, Virolle, Thierry, Goodhardt, Michele, Chneiweiss, Hervé, Junier, Marie-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773658/
https://www.ncbi.nlm.nih.gov/pubmed/29149419
http://dx.doi.org/10.1007/s00401-017-1783-x

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