Cargando…

Dosimetric Validation of Volumetric Modulated Arc Therapy (VMAT) Using AAPM TG-119 Benchmark Plans in an Upgraded CLINAC 2100CD for Flattening Filter Free (FFF) Photon Beams

BACKGROUND: Recently we have upgraded our Varian Clinac 2100CD with a 6MV FFF beam, this upgrade being the first of its kind in our country. Even though the dosimetric characteristics of FFF beams have been reported both in experimental and Monte Carlo studies, application in planning and delivery i...

Descripción completa

Detalles Bibliográficos
Autores principales: Sangaiah, Ashokkumar, Ganesh, K M, Ramalingam, K, Karthikeyan, K, Jagadheeskumar, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773778/
https://www.ncbi.nlm.nih.gov/pubmed/29172266
http://dx.doi.org/10.22034/APJCP.2017.18.11.2965
_version_ 1783293633115455488
author Sangaiah, Ashokkumar
Ganesh, K M
Ramalingam, K
Karthikeyan, K
Jagadheeskumar, N
author_facet Sangaiah, Ashokkumar
Ganesh, K M
Ramalingam, K
Karthikeyan, K
Jagadheeskumar, N
author_sort Sangaiah, Ashokkumar
collection PubMed
description BACKGROUND: Recently we have upgraded our Varian Clinac 2100CD with a 6MV FFF beam, this upgrade being the first of its kind in our country. Even though the dosimetric characteristics of FFF beams have been reported both in experimental and Monte Carlo studies, application in planning and delivery is complex. The aim of this study was to validate the commissioning of upgraded FFF beams dosimetrically using AAPM TG-119 bench mark plans for VMAT and to make a comparison with IMRT plans for both flattened filtered and FFF beams. MATERIALS AND METHODS: AAPM TG-119 proposes a set of test clinical cases for testing the accuracy of IMRT planning and delivery systems. For these clinical cases we generated four treatment plans using IMRT FF, IMRT FFF, VMAT FF and VMAT FFF on a Varian Clinac 2100CD machine equipped with a millennium 120 MLC in Eclipse treatment planning system. Dose prescription and planning objectives were set according to the TG-119 goals and plans were scored based on planning objectives. Plans were compared using dose coverage, the conformity index and the homogeneity index. Point doses were measured at points recommended by TG-119 using a CC13 ion chamber. Planar dosimetry was accomplished using Imatrix and gamma evaluation was conducted using Omnipro IMRT software. RESULTS: Dose distributions of FFF beam based plans were comparable to FF plans for both IMRT and VMAT. Our planning results matched TG-119 planning results. Measured point doses were within ±2% of planned doses and planar dosimetry gamma values were <1 for >95% of data points for all plans. CONCLUSION: We found a reduction of 40% treatment time for FFF against FF beams for sliding window IMRT. Upgraded FFF beams were in good agreement with TG-119 benchmark plans and goals.
format Online
Article
Text
id pubmed-5773778
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher West Asia Organization for Cancer Prevention
record_format MEDLINE/PubMed
spelling pubmed-57737782018-02-01 Dosimetric Validation of Volumetric Modulated Arc Therapy (VMAT) Using AAPM TG-119 Benchmark Plans in an Upgraded CLINAC 2100CD for Flattening Filter Free (FFF) Photon Beams Sangaiah, Ashokkumar Ganesh, K M Ramalingam, K Karthikeyan, K Jagadheeskumar, N Asian Pac J Cancer Prev Research Article BACKGROUND: Recently we have upgraded our Varian Clinac 2100CD with a 6MV FFF beam, this upgrade being the first of its kind in our country. Even though the dosimetric characteristics of FFF beams have been reported both in experimental and Monte Carlo studies, application in planning and delivery is complex. The aim of this study was to validate the commissioning of upgraded FFF beams dosimetrically using AAPM TG-119 bench mark plans for VMAT and to make a comparison with IMRT plans for both flattened filtered and FFF beams. MATERIALS AND METHODS: AAPM TG-119 proposes a set of test clinical cases for testing the accuracy of IMRT planning and delivery systems. For these clinical cases we generated four treatment plans using IMRT FF, IMRT FFF, VMAT FF and VMAT FFF on a Varian Clinac 2100CD machine equipped with a millennium 120 MLC in Eclipse treatment planning system. Dose prescription and planning objectives were set according to the TG-119 goals and plans were scored based on planning objectives. Plans were compared using dose coverage, the conformity index and the homogeneity index. Point doses were measured at points recommended by TG-119 using a CC13 ion chamber. Planar dosimetry was accomplished using Imatrix and gamma evaluation was conducted using Omnipro IMRT software. RESULTS: Dose distributions of FFF beam based plans were comparable to FF plans for both IMRT and VMAT. Our planning results matched TG-119 planning results. Measured point doses were within ±2% of planned doses and planar dosimetry gamma values were <1 for >95% of data points for all plans. CONCLUSION: We found a reduction of 40% treatment time for FFF against FF beams for sliding window IMRT. Upgraded FFF beams were in good agreement with TG-119 benchmark plans and goals. West Asia Organization for Cancer Prevention 2017 /pmc/articles/PMC5773778/ /pubmed/29172266 http://dx.doi.org/10.22034/APJCP.2017.18.11.2965 Text en Copyright: © Asian Pacific Journal of Cancer Prevention http://creativecommons.org/licenses/BY-SA/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
spellingShingle Research Article
Sangaiah, Ashokkumar
Ganesh, K M
Ramalingam, K
Karthikeyan, K
Jagadheeskumar, N
Dosimetric Validation of Volumetric Modulated Arc Therapy (VMAT) Using AAPM TG-119 Benchmark Plans in an Upgraded CLINAC 2100CD for Flattening Filter Free (FFF) Photon Beams
title Dosimetric Validation of Volumetric Modulated Arc Therapy (VMAT) Using AAPM TG-119 Benchmark Plans in an Upgraded CLINAC 2100CD for Flattening Filter Free (FFF) Photon Beams
title_full Dosimetric Validation of Volumetric Modulated Arc Therapy (VMAT) Using AAPM TG-119 Benchmark Plans in an Upgraded CLINAC 2100CD for Flattening Filter Free (FFF) Photon Beams
title_fullStr Dosimetric Validation of Volumetric Modulated Arc Therapy (VMAT) Using AAPM TG-119 Benchmark Plans in an Upgraded CLINAC 2100CD for Flattening Filter Free (FFF) Photon Beams
title_full_unstemmed Dosimetric Validation of Volumetric Modulated Arc Therapy (VMAT) Using AAPM TG-119 Benchmark Plans in an Upgraded CLINAC 2100CD for Flattening Filter Free (FFF) Photon Beams
title_short Dosimetric Validation of Volumetric Modulated Arc Therapy (VMAT) Using AAPM TG-119 Benchmark Plans in an Upgraded CLINAC 2100CD for Flattening Filter Free (FFF) Photon Beams
title_sort dosimetric validation of volumetric modulated arc therapy (vmat) using aapm tg-119 benchmark plans in an upgraded clinac 2100cd for flattening filter free (fff) photon beams
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773778/
https://www.ncbi.nlm.nih.gov/pubmed/29172266
http://dx.doi.org/10.22034/APJCP.2017.18.11.2965
work_keys_str_mv AT sangaiahashokkumar dosimetricvalidationofvolumetricmodulatedarctherapyvmatusingaapmtg119benchmarkplansinanupgradedclinac2100cdforflatteningfilterfreefffphotonbeams
AT ganeshkm dosimetricvalidationofvolumetricmodulatedarctherapyvmatusingaapmtg119benchmarkplansinanupgradedclinac2100cdforflatteningfilterfreefffphotonbeams
AT ramalingamk dosimetricvalidationofvolumetricmodulatedarctherapyvmatusingaapmtg119benchmarkplansinanupgradedclinac2100cdforflatteningfilterfreefffphotonbeams
AT karthikeyank dosimetricvalidationofvolumetricmodulatedarctherapyvmatusingaapmtg119benchmarkplansinanupgradedclinac2100cdforflatteningfilterfreefffphotonbeams
AT jagadheeskumarn dosimetricvalidationofvolumetricmodulatedarctherapyvmatusingaapmtg119benchmarkplansinanupgradedclinac2100cdforflatteningfilterfreefffphotonbeams